The following table lists the limitations when Security Agents only have an IPv6 address.
Item  | 
Limitation  | 
|---|---|
Parent server  | 
Pure IPv6 agents cannot be managed by a pure IPv4 server.  | 
Updates  | 
A pure IPv6 agent cannot update from pure IPv4 update sources, such as: 
  | 
Web Reputation queries  | 
A pure IPv6 agent cannot send Web Reputation queries to Trend Micro Smart Protection Network.  | 
Proxy connection  | 
A pure IPv6 agent cannot connect through a pure IPv4 proxy server.  | 
Agent deployment  | 
Apple Remote Desktop is unable to deploy the agent to pure IPv6 endpoints because these endpoints always appear as offline.  | 
Most of these limitations can be overcome by setting up a dual-stack proxy server that can convert between IPv4 and IPv6 addresses (such as DeleGate). Position the proxy server between the agents and the entities to which they connect.
		